College Football Week 10 Schedule and Odds: Month-long Fall Feast Begins With Five Straight Days of CFB Action

Tonight brings the reveal of the first College Football Playoff rankings of the season, but that isn’t the only thing to look forward to on the college football front tonight.

Tonight also brings the start of this week’s college football action, and it also kicks off a football feast. Over the remainder of November, there will be only two days without at least one major college football or NFL game: the 24th and the 30th.

That means that we have not one, not two, not three, but four weeks of midweek MACtion to look forward to, starting tonight with three games. If that doesn’t get you excited, you’re in the wrong place right now.

Let’s take a look at the week that will be in major college football. There may be only one game featuring two ranked teams–#12 Auburn visits #13 Texas A&M–but there a number of intriguing matchups and potential problem spots for ranked teams.

College Football Week 10 Schedule and Odds Menu

• College Football Week 10 Schedule
• Week 10 Top Betting Matchups and Odds

College Football Week 10 Schedule

• American Athletic Conference
• ACC
• Big 12
• Big Ten
• Conference USA
• Mid-American Conference
• Mountain West
• Pac-12
• SEC
• Sun Belt
• FBS Independents & Non-Conference Matchups

American Athletic Conference

Cincinnati hasn’t looked great in their last two games, so a blowout of Tulsa this weekend would be a welcome result for the Bearcats and their hopes of ending up in the College Football Playoff.

Saturday, November 6

#23 SMU (7-1, 3-1 AAC) vs Memphis (4-4, 1-3 AAC), ESPNU, 12:00 p.m. ET

Temple (3-5, 1-3 AAC) vs East Carolina (4-4, 2-2 AAC), ESPN+, 3:00 p.m. ET

Tulsa (3-5, 2-2 AAC) vs #2 Cincinnati (8-0, 4-0 AAC), ESPN2, 3:30 p.m. ET

Tulane (1-7, 0-4 AAC) vs UCF (5-3, 3-2 AAC), ESPNU, 4:00 p.m. ET

#24 Houston (7-1, 4-0 AAC) vs USF (2-6, 1-3 AAC), ESPNU, 7:30 p.m. ET

ACC

The ACC’s College Football Playoff hopes could be ended this weekend in what should be a shootout in Chapel Hill. North Carolina hasn’t lived up to preseason expectations, but a win over undefeated Wake Forest would be a reminder of why the Tar Heels were so highly thought of entering the season.

Friday, November 5

Virginia Tech (4-4, 2-2 ACC) vs Boston College (4-4, 0-4 ACC), ESPN2, 7:30 p.m. ET

Saturday, November 6

#10 Wake Forest (8-0, 5-0 ACC) vs North Carolina (4-4, 3-3 ACC), ABC, 12:00 p.m. ET

Pittsburgh (6-2, 3-1 ACC) vs Duke (3-5, 0-4 ACC), ACC Network, 12:00 p.m. ET

Georgia Tech (3-5, 2-4 ACC) vs Miami (4-4, 2-2 ACC), ESPN3, 12:00 p.m. ET

North Carolina State (6-2, 3-1 ACC) vs Florida State (3-5, 2-3 ACC), ACC Network, 4:00 p.m. ET

Clemson (5-3, 4-2 ACC) vs Louisville (4-4, 2-3 ACC), ACC Network, 7:30 p.m. ET

Big 12

It will take a lot for the Big 12 to get two teams in the College Football Playoff, but all Baylor and Oklahoma State can do is win. They both have road trips to navigate this week.

Saturday, November 6

Kansas State (5-3, 2-3 Big 12) vs Kansas (1-7, 0-5 Big 12), Fox Sports 1, 12:00 p.m. ET

#11 Oklahoma State (7-1, 4-1 Big 12) vs West Virginia (4-4, 2-3 Big 12), ESPN2, 3:30 p.m. ET

#14 Baylor (7-1, 4-1 Big 12) vs TCU (3-5, 1-4 Big 12), FOX, 3:30 p.m. ET

Texas (4-4, 2-3 Big 12) vs #22 Iowa State (5-3, 3-2 Big 12), Fox Sports 1, 7:30 p.m. ET

Big Ten

As big as Michigan State’s thrilling comeback win over archrival Michigan was, it won’t matter all that much if the Spartans trip themselves up at Purdue on Saturday. Michigan State needs to be 10-0 when they travel to Ohio State on November 20 for a matchup that will be key for the Big Ten title and College Football Playoff.

Saturday, November 6

#6 Ohio State (7-1, 5-0 Big Ten) vs Nebraska (3-6, 1-5 Big Ten), FOX, 12:00 p.m. ET

Illinois (3-6, 2-4 Big Ten) vs Minnesota (6-2, 4-1 Big Ten), ESPN2, 12:00 p.m. ET

#5 Michigan State (8-0, 5-0 Big Ten) vs Purdue (5-3, 3-2 Big Ten), ABC, 3:30 p.m. ET

#22 Penn State (5-3, 2-3 Big Ten) vs Maryland (5-3, 2-3 Big Ten), Fox Sports 1, 3:30 p.m. ET

Wisconsin (5-3, 3-2 Big Ten) vs Rutgers (4-4, 1-4 Big Ten), Big Ten Network, 3:30 p.m. ET

#19 Iowa (6-2, 3-2 Big Ten) vs Northwestern (3-5, 1-4 Big Ten), 7:00 p.m. ET

Indiana (2-6, 1-5 Big Ten) vs #9 Michigan (7-1, 4-1 Big Ten), FOX, 7:30 p.m. ET

Conference USA

UTEP’s loss to FAU took some luster off of UTSA’s visit to El Paso, but it is still a huge game nonetheless with the Roadrunners eyeing a perfect season.

Saturday, November 6

Louisiana Tech (2-6, 1-3 C-USA) vs UAB (5-3, 3-1 C-USA), CBS Sports Network, 12:00 p.m. ET

North Texas (2-6, 1-3 C-USA) vs Southern Miss (1-7, 0-4 C-USA), ESPN+, 3:00 p.m. ET

Rice (3-5, 2-2 C-USA) vs Charlotte (4-4, 2-2 C-USA), ESPN+, 3:30 p.m. ET

Middle Tennessee (4-4, 2-2 C-USA) vs Western Kentucky (4-4, 3-1 C-USA), 3:30 p.m. ET

Marshall (5-3, 3-1 C-USA) vs FAU (5-3, 3-1 C-USA), 6:00 p.m. ET

Old Dominion (2-6, 1-3 C-USA) vs FIU (1-7, 0-4 C-USA), ESPN3, 7:00 p.m. ET

#16 UTSA (8-0, 4-0 C-USA) vs UTEP (6-2, 3-1 C-USA), ESPN2, 10:15 p.m. ET

Mid-American

Tuesday and Wednesday MACtion? Say no more.

Tuesday, November 2

Ball State (4-4, 2-2 MAC) vs Akron (2-6, 1-3 MAC), CBS Sports Network, 7:00 p.m. ET

Miami (Ohio) (4-4, 3-1 MAC) vs Ohio (1-7, 1-3 MAC), ESPNU, 7:30 p.m. ET

Eastern Michigan (5-3, 2-2 MAC) vs Toledo (4-4, 2-2 MAC), ESPN2, 7:30 p.m. ET

Wednesday, November 3

Central Michigan (4-4, 2-2 MAC) vs Western Michigan (5-3, 2-2 MAC), ESPNU, 7:00 p.m. ET

Northern Illinois (6-2, 4-0 MAC) vs Kent State (4-4, 3-1 MAC), ESPN2, 7:00 p.m. ET

Mountain West

Fresno State is in the top 25 of the college football rankings once again after ending San Diego State’s undefeated season with an impressive road win over the Aztecs. How long will their stay be this time? It could be another short stint if Boise State shakes their pattern of alternating losses and wins this season.

Saturday, November 6

Colorado State (3-5, 2-2 Mountain West) vs Wyoming (4-4, 0-4 Mountain West), CBS Sports Network, 3:30 p.m. ET

Boise State (4-4, 2-2 Mountain West) vs #25 Fresno State (7-2, 4-1 Mountain West), CBS Sports Network, 7:00 p.m. ET

UNLV (0-8, 0-4 Mountain West) vs New Mexico (3-5, 1-3 Mountain West), 7:00 p.m. ET

San Jose State (5-4, 3-2 Mountain West) vs Nevada (6-2, 3-1 Mountain West), Fox Sports 2, 10:00 p.m. ET

San Diego State (7-1, 3-1 Mountain West) vs Hawaii (4-5, 1-3 Mountain West), Fox Sports 1, 11:00 p.m. ET

Pac-12

Thanks to the below bumbling, stumbling comments by Washington coach Jimmy Lake, Oregon’s visit to Seattle has a little more spice to it. Can the Huskies make things interesting, or will the Ducks show their prowess on the field?

#Washington coach Jimmy Lake, asked today if #Oregon is a recruiting rival. Woo boy pic.twitter.com/7vHFQi96yp

— Adam Rittenberg (@ESPNRittenberg) November 1, 2021

Friday, November 5

Utah (5-3, 4-1 Pac-12) vs Stanford (3-5, 2-4 Pac-12), Fox Sports 1, 10:30 p.m. ET

Saturday, November 6

Cal (3-5, 2-3 Pac-12) vs Arizona (0-8, 0-5 Pac-12), Pac-12 Network, 3:00 p.m. ET

Oregon State (5-3, 3-2 Pac-12) vs Colorado (2-6, 1-4 Pac-12), Pac-12 Network, 7:00 p.m. ET

#7 Oregon (7-1, 4-1 Pac-12) vs Washington (4-4, 3-2 Pac-12), ABC, 7:30 p.m. ET

USC (4-4, 3-3 Pac-12) vs Arizona State (5-3, 3-2 Pac-12), ESPN, 10:30 p.m. ET

SEC

While it’s LSU-Alabama week, the spotlight matchup in the SEC is Auburn’s trip to College Station, which is the only ranked vs ranked game on this week’s college football schedule.

Saturday, November 6

Missouri (4-4, 1-3 SEC) vs #1 Georgia (8-0, 6-0 SEC), ESPN, 12:00 p.m. ET

#12 Auburn (6-2, 3-1 SEC) vs #13 Texas A&M (6-2, 3-2 SEC), CBS, 3:30 p.m. ET

Mississippi State (5-3, 3-2 SEC) vs Arkansas (5-3, 1-3 SEC), SEC Network, 4:00 p.m. ET

LSU (4-4, 2-3 SEC) vs #3 Alabama (7-1, 4-1 SEC), ESPN, 7:00 p.m. ET

Tennessee (4-4, 2-3 SEC) vs #18 Kentucky (6-2, 4-2 SEC), ESPN2, 7:00 p.m. ET

Florida (4-4, 2-4 SEC) vs South Carolina (4-4, 1-4 SEC), SEC Network, 7:30 p.m. ET

Sun Belt

We now have two ranked teams in the Sun Belt, with Louisiana joining Coastal Carolina in the top 25 in this week’s AP poll. With Appalachian State receiving votes in both major college football polls, that number could increase soon.

Thursday, November 4

Georgia State (4-4, 3-1 Sun Belt) vs #24 Louisiana (7-1, 5-0 Sun Belt), ESPN, 7:30 p.m. ET

Saturday, November 6

Appalachian State (6-2, 3-1 Sun Belt) vs Arkansas State (1-7, 0-4 Sun Belt), ESPN+, 2:00 p.m. ET

UL Monroe (4-4, 2-3 Sun Belt) vs Texas State (2-6, 1-3 Sun Belt), ESPN+, 3:00 p.m. ET

South Alabama (5-3, 2-3 Sun Belt) vs Troy (4-4, 2-2 Sun Belt), ESPN+, 3:30 p.m. ET

#21 Coastal Carolina (7-1, 3-1 Sun Belt) vs Georgia Southern (2-6, 1-4 Sun Belt), ESPN+, 6:00 p.m. ET

FBS Independents & Non-Conference Matchups

One of the more interesting college football lines this week is the total for the Army-Air Force matchup in Arlington. When Army last took the field, they put up 56 points in a losing effort against Wake Forest. The total for their rivalry showdown with the Falcons is almost three touchdowns less than that.

Saturday, November 6

Army (4-3) vs Air Force (6-2), CBS, 11:30 a.m. ET (at Choctaw Stadium in Arlington, Texas)

Liberty (7-2) vs #15 Ole Miss (6-2), SEC Network, 12:00 p.m. ET

Idaho State (1-7) vs #17 BYU (7-2), ESPN3, 3:00 p.m. ET

Rhode Island (5-3) vs UMass (1-7), 3:30 p.m. ET

Navy (2-6) vs #8 Notre Dame (7-1), NBC, 3:30 p.m. ET

Utah State (6-2) vs New Mexico State (1-7), 4:00 p.m. ET

College Football Week 10 Top Betting Matchups and Odds

All odds listed below are via BetOnline Sportsbook as of Tuesday, November 2, 2021 at 2:40 p.m. ET.

As much as we’d like to cover every single one of the college football matchups that we have our eye on, there are only so many hours in the week. So here’s a quick rundown of the matchups we will be providing in-depth previews for this week on Betting News.

College Football Betting Matchup: Eastern Michigan at Toledo

Eastern Michigan-Toledo Odds

• Spread: Eastern Michigan +8.5 (-110), Toledo -8.5 (-112)
• Total: OVER 54.5 (-106), UNDER 54.4 (-114)
• Moneyline: Eastern Michigan +270, Toledo -355

College Football Betting Odds: Northern Illinois at Kent State

Northern Illinois-Kent State Odds

• Spread: Northern Illinois +3.5 (-108), Kent State -3.5 (-112)
• Total: OVER 66.5 (-106), UNDER 66.5 (-114)
• Moneyline: Northern Illinois +148, Kent State -184

College Football Betting Matchup: Georgia State at Louisiana

Georgia State-Louisiana Odds

• Spread: Georgia State +12.5 (-110), Louisiana -12.5 (-110)
• Total: OVER 54.5 (-110), UNDER 54.5 (-110)
• Moneyline: Georgia State +390, Louisiana -550

College Football Betting Odds: Utah at Stanford

Utah-Stanford Odds

• Spread: Utah -7.5 (+100), Stanford +7.5 (-122)
• Total: OVER 53.5 (-114), UNDER 53.5 (-106)
• Moneyline: Utah -290, Stanford +220

College Football Betting Matchup: Army vs Air Force

Army-Air Force Odds

• Spread: Army +2.5 (-104), Air Force -2.5 (-118)
• Total: OVER 36.5 (-114), UNDER 36.5 (-106)
• Moneyline: Army +122, Air Force -150

College Football Betting Matchup: Missouri at Georgia

Missouri-Georgia Odds

• Spread: Missouri +37.5 (-106), Georgia -37.5 (-114)
• Total: OVER 59.5 (-105), UNDER 59.5 (-115)
• Moneyline: Missouri +4000, Georgia -100000

College Football Betting Matchup: Ohio State at Nebraska

Ohio State-Nebraska Odds

• Spread: Ohio State -14.5 (-112), Nebraska +14.5 (-110)
• Total: OVER 64.5 (-110), UNDER 64.5 (-110)
• Moneyline: Ohio State -650, Nebraska +440

College Football Betting Matchup: Liberty at Ole Miss

Liberty-Ole Miss Odds

• Spread: Liberty +8.5 (-108), Ole Miss -8.5 (-112)
• Total: OVER 68.5 (-112), UNDER 68.5 (-110)
• Moneyline: Liberty +310, Ole Miss -420

College Football Betting Matchup: Wake Forest at North Carolina

Wake Forest-North Carolina Odds

• Spread: Wake Forest +2.5 (-106), North Carolina -2.5 (-114)
• Total: OVER 76.5 (-114), UNDER 76.5 (-106)
• Moneyline: Wake Forest +116, North Carolina -142

College Football Betting Matchup: Tulsa at Cincinnati

Tulsa-Cincinnati Odds

• Spread: Tulsa +22.5 (-110), Cincinnati -22.5 (-110)
• Total: OVER 54.5 (-106), UNDER 54.5 (-114)
• Moneyline: Tulsa +1120, Cincinnati -3000

College Football Betting Matchup: Michigan State at Purdue

Michigan State-Purdue Odds

• Spread: Michigan State -2.5 (-128), Purdue +2.5 (+104)
• Total: OVER 54.5 (-105), UNDER 54.5 (-115)
• Moneyline: Michigan State -160, Purdue +130

College Football Betting Matchup: Auburn at Texas A&M

Auburn-Texas A&M

• Spread: Auburn +4.5 (-112), Texas A&M -4.5 (-108)
• Total: OVER 50.5 (-106), UNDER 50.5 (-114)
• Moneyline: Auburn +172, Texas A&M -215

College Football Betting Matchup: Oklahoma State at West Virginia

Oklahoma State-West Virginia

• Spread: Oklahoma State -2.5 (-120), West Virginia +2.5 (-102)
• Total: OVER 49.5 (-108), UNDER 49.5 (-112)
• Moneyline: Oklahoma State -150, West Virginia +122

College Football Betting Matchup: Baylor at TCU

Baylor-TCU Odds

• Spread: Baylor -6.5 (-110), TCU +6.5 (-110)
• Total: OVER 58.5 (-114), UNDER 58.5 (-106)
• Moneyline: Baylor -250, TCU +198

College Football Betting Matchup: LSU at Alabama

LSU-Alabama Odds

• Spread: LSU +28.5 (-108), Alabama -28.5 (-112)
• Total: OVER 66.5 (-105), UNDER 66.5 (-115)
• Moneyline: LSU +1300, Alabama -4500

College Football Betting Matchup: Boise State at Fresno State

Boise State-Fresno State Odds

• Spread: Boise State +4.5 (-106), Fresno State -4.5 (-114)
• Total: OVER 58.5 (-110), UNDER 58.5 (-110)
• Moneyline: Boise State +172, Fresno State -215

College Football Betting Matchup: Oregon at Washington

Oregon-Washington Odds

• Spread: Oregon -6.5 (-114), Washington +6.5 (-106)
• Total: OVER 51.5 (-104), UNDER 51.5 (-118)
• Moneyline: Oregon -265, Washington +210

College Football Betting Matchup: UTSA at UTEP

UTSA-UTEP Odds

• Spread: UTSA -11.5 (-106), UTEP +11.5 (-114)
• Total: OVER 52.5 (-114), UNDER 52.5 (-106)
• Moneyline: UTSA -500, UTEP +360

College Football Betting Matchup: San Diego State at Hawaii

San Diego State-Hawaii Odds

• Spread: San Diego State -7.5 (-105), Hawaii +7.5 (-115)
• Total: OVER 46.5 (-110), UNDER 46.5 (-110)
• Moneyline: San Diego State -325, Hawaii +250