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49ers vs Eagles Prediction, Odds, Spread & Picks | NFL Week 13: NFC Championship Preview
Written by: Devon Platana
Last Updated:
Read Time: 6 minutes
nfl
San Francisco 49ers Odds
Spread
Total
Moneyline
-4.5
-115
39
-120o
-275
Philadelphia Eagles Odds
Spread
Total
Moneyline
+7.5
-110
43
-110u
+290
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See Picks & Statistics For The GameBetting News has been covering the NFL Week 13 schedule throughout the week and our next stop is the Sunday afternoon showdown between the San Francisco 49ers and Philadelphia Eagles at 4:25 p.m. ET.
The 49ers are riding a momentum wave, extending their winning streak to three games with a 31-13 victory over the rival Seattle Seahawks last week. Meanwhile, the Eagles have won five games in a row, most recently edging the Buffalo Bills 37-34 in overtime.
Unsurprisingly, these are two of the most popular picks to win Super Bowl LVIII. Philadelphia is BetOnline’s +410 favorite to hoist the Lombardi Trophy in February while San Francisco is right behind in second at +425 odds.
If you’re looking to wager on this game, this article is for you. Strap in and keep scrolling to read all about my 49ers vs Eagles prediction, the latest NFL odds, and the best bets you can make.
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49ers vs Eagles Betting Preview — NFL Week 13
49ers vs Eagles Matchup Information
- Matchup: San Francisco 49ers (8-3, 4-2 Away) vs. Philadelphia Eagles (10-1, 5-0 Home)
- Venue & Location: Lincoln Financial Field (Philadelphia, PA)
- Date: Sunday, Dec. 3, 2023
- Game Time: 4:25 p.m. ET
- 49ers vs. Eagles Week 13 TV Channel: FOX
49ers vs Eagles Odds & Spread
NFL game odds courtesy of BetOnline as of Wednesday, Nov. 29 at 9:19 a.m. ET. Odds from other sportsbooks may also be mentioned in this article.
49ers vs Eagles Spread
- San Francisco 49ers -3 (+100)
- Philadelphia Eagles +3 (-120)
49ers vs Eagles Over/Under
- Over 46.5 Points (-105)
- Under 46.5 Points (-115)
49ers vs Eagles Moneyline
- San Francisco 49ers (-155)
- Philadelphia Eagles (+135)
Updated 49ers vs Eagles Odds & Spread
Updated odds as of 12:05 p.m. ET on Sunday, Dec. 3.
49ers vs Eagles Spread
- San Francisco 49ers -3 (-103)
- Philadelphia Eagles +3 (-117)
49ers vs Eagles Over/Under
- Over 47 Points (-105)
- Under 47 Points (-115)
49ers vs Eagles Moneyline
- San Francisco 49ers (-147)
- Philadelphia Eagles (+127)
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49ers vs Eagles Betting Trends
- San Francisco is 3-8 straight up in its last 11 games vs. Philadelphia.
- Philadelphia is 7-1 straight up in its last eight home games.
- San Francisco is 6-1 ATS in its last seven games played in December.
- Philadelphia is 9-2 ATS in its last 11 games vs. San Francisco.
- The total hit the Under in four of San Francisco’s last five road games vs. Philadelphia.
- The total hit the Under in six of Philadelphia’s last seven games vs. the NFC West.
49ers vs Eagles Prediction & Best Bet: NFL Week 13 Betting
Not only is this clash a potential NFC Championship Game preview, but it’s also a rematch of last season’s conference title showdown.
The 49ers and Eagles last met at Lincoln Financial Field on Jan. 29 in a game that wasn’t even close. Philadelphia emerged victorious with a 31-7 blowout win after San Francisco QB Brock Purdy left the game early with a UCL injury, playing a role in the visitors’ motivation to win this weekend.
Nevertheless, it’s interesting to see the Eagles as home underdogs in Week 13. After all, the only other time they were underdogs at all this season was when they faced the Kansas City Chiefs in Week 11. As everyone knows, Nick Sirianni’s team pulled off the upset in that one.
With that in mind, the Eagles head into this matchup with an 8-3 ATS record (including 5-0 ATS at home), whereas the 49ers are just 5-5-1 ATS and have only covered in three of five road games thus far.
It’s worth noting that the Eagles have yet to lose at Lincoln Financial Field this season. They average the third-most points at home while allowing the sixth-fewest, resulting in a plus-6.2 average scoring margin — good for ninth-best in the NFL.
At the same time, while they haven’t been perfect on the road, the 49ers still own a league-best plus-13.6 margin in away games.
Still, that doesn’t change the fact that San Francisco has lost four of its last six road games against Philadelphia. The 49ers only averaged 8.3 PPG in those losses, losing each by at least 14 points.
The 49ers are much healthier than they were in January, meaning this game will be close. Having said that, I’m still taking the Eagles to win. Philadelphia is white-hot at home and even though they aren’t blowing every team out, they still find ways to beat the best that the NFL has to offer and San Francisco won’t be any different.
Still, this game could go either way, which is why I’m inclined to back the Under on the 46.5-point total as a neutral bet. After all, we’re dealing with two of the best defenses that football has to offer when they’re on their game.
Additionally, the Under has hit in each of the last five 49ers-Eagles clashes, averaging a total of 40.2 points while finishing with fewer than 46.5 in each of the last four.
49ers vs Eagles Prediction: PHI wins
49ers vs Eagles Best Bet: u47 Total Points (-115 on BetOnline)
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Best 49ers vs Eagles Player Prop: NFL Week 13 Betting
Hopping over to Bovada for the best 49ers vs. Eagles player prop, let’s go with Brandon Aiyuk finishing with Over 60.5 receiving yards.
The 49ers wideout is experiencing his best season to date, averaging a career-high 88.1 receiving yards per game. He’s finished with the Over on this prop in five of 10 outings thus far, which includes four 100-yard performances.
The good news for Aiyuk is that the Eagles allow the third-most yards to receivers and have surrendered 300-plus passing yards in three of their last four games. In other words, finishing with at least 61 receiving yards shouldn’t be an issue.
Best 49ers vs Eagles Player Prop: Brandon Aiyuk o60.5 Receiving Yards (-115 on BetOnline)
49ers vs Eagles Week 13 FAQ
When is 49ers vs Eagles?
- The 49ers and Eagles will collide on Sunday, Dec. 3, 2023.
Where is 49ers vs Eagles?
- The 49ers and eagles will play each other at Lincoln Financial Field in Philadelphia, PA.
What time does 49ers vs Eagles start?
- Kickoff for the upcoming SF vs. PHI matchup is slated for 4:25 p.m. ET.
How can I watch 49ers vs Eagles?
- 49ers and Eagles fans can tune in to FOX for Sunday’s game.
How to Bet on 49ers vs Eagles
- Most reputable sportsbooks — including BetDSI — offer 49ers vs. Eagles betting markets and the rest of the NFL Week 13 slate.
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Devon is a Master of Journalism graduate who joined the sports betting world in 2020. His favorite leagues to cover are the NHL, NBA and NFL, and has a soft spot for fantasy football specifically. Outside of sports, he enjoys the finer things in life like pasta, live music and getting even more tattoos.
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