Broncos vs. Chargers Week 6 Betting: Can Denver Pull of Road Upset Against AFC West Rival?

Week 6 of the 2022 NFL season is here, leaving fans and bettors with no shortage of exciting games to anticipate. One matchup that many folks have circled is an AFC West showdown between the Denver Broncos and Los Angeles Chargers, which happens to serve as this week’s Monday Night Football game.

The #Broncos have already been on primetime three times in five weeks to start the season.

And … they're back on primetime again next Monday night against the Chargers.

— Ari Meirov (@MySportsUpdate) October 7, 2022

The Broncos gave fans very little to cheer about during last week’s 12-9 overtime loss to the Indianapolis Colts. Denver’s offense continued to look like a disaster, going 2-of-15 on third-down conversions while Russell Wilson also threw two interceptions in the loss.

Meanwhile, the Chargers look to build upon the momentum that comes from their 30-28 victory over the Cleveland Browns in Week 5. Running back Austin Ekeler did most of his team’s damages, tallying 199 total yards from scrimmage and two touchdowns on 20 touches.

Betting News has gathered the latest Broncos vs Chargers odds from BetOnline Sportsbook to help shed some light on the situation, along with a prediction and best bets for the NFL Week 6 game.

Denver Broncos vs Los Angeles Chargers Week 6 Matchup Information and Betting Odds

Matchup Information

• Matchup: Denver Broncos (2-3, 0-2 Away) vs. Los Angeles Chargers (3-2, 1-1 Home)
• Venue & Location: SoFi Stadium (Inglewood, California)
• Date: Monday, Oct. 17, 2022
• Game Time: 8:15 p.m. Eastern Time
• Broncos vs Chargers Info: NBC

Broncos vs Chargers Odds

Game odds are via BetOnline as of Tuesday, Oct. 11 at 8:29 a.m. ET. Odds from other top online sportsbooks may also be mentioned in this article.

Spread

• Denver Broncos +4.5 (-105)
• Los Angeles Chargers -4.5 (-115)

Over/Under

• Over 45.5 Points (-110)
• Under 45.5 Points (-110)

Moneyline

• Denver Broncos +190
• Los Angeles Chargers -230

Denver Broncos vs Los Angeles Chargers Betting Trends

• Denver is 1-7 straight up in its last eight games played in October.
• The Chargers are 5-12 straight up in their last 17 games against Denver.
• Denver is 0-5 against the spread (ATS) in its last five road games.
• The Chargers are 8-3 ATS in their last 11 games against the AFC West.
• The total has hit the under in eight of Denver’s last nine road games against the Chargers.
• The total has hit the over in nine of the Chargers’ last 11 games.

Denver Broncos vs Los Angeles Chargers Prediction and Picks

Broncos vs Chargers Prediction: Chargers 30, Broncos 17

Broncos vs Chargers Picks: Chargers -4.5 (Best Value: -115 at BetOnline) & Over 45.5 Points (Best Value: -110 at BetOnline)

The AFC West was expected to be a bloodbath this season. Instead, one can make the argument that the Kansas City Chiefs are the only team in the division to live up to expectations this season.

Having said that, the Chargers have gotten back on track over the last two weeks. It hasn’t been pretty, but Brandon Staley’s team has now won back-to-back games. The same can’t be said for the Broncos, who’ve lost two in a row now.

For Denver, its biggest problem has been a lack of offensive production. The Broncos only average 15.0 points (No. 31) and 1.2 touchdowns (T-No. 31) through five games thus far.

Meanwhile, the Chargers have averaged 24.4 points per game (No. 9) while generating a whopping 390.4 yards (No. 5). Even with the defensive struggles that Los Angeles has dealt with, the offense is more than talented enough to balance things out.

While Denver’s defense has shown promise at times, the unit did surrender 32 points to the Las Vegas Raiders just two weeks ago. Considering how explosive Justin Herbert and his weapons can be at times, the Chargers should be just fine.

It’s just hard to imagine the Broncos matching their opponent’s offense — especially with Wilson’s struggles. The veteran gunslinger has completed a career-worst 59.4% of his passes for 1,254 yards and four touchdowns to three interceptions, which isn’t exactly the version of Wilson that the Broncos assumed they were getting.

It’s also tougher for the Broncos to rely on their backfield now that Javonte Williams is out. The duo of Melvin Gordon and Mike Boone combined for 92 yards on 22 carries last week, but neither man provided much of an impact.

At the end of the day, the Broncos have done themselves no favors to get the benefit of the doubt here. They just don’t look like that good of a team or maybe Nathaniel Hackett isn’t the right guy to have behind the bench.

Besides, the Chargers have won their last two home games against the Broncos by a combined score of 53-29. Considering how the Broncos have also lost seven of their last eight road games in general, I like Los Angeles’ chances to score a win against its rival.

I’m also willing to back the total hitting the over on Monday. While the Chargers’ offense is world-class, their defense could use some work. The Broncos might be bad at scoring the ball, but they should still find some success against Los Angeles. Still, expect the Chargers to do most of the heavy lifting.

NFL Futures Articles on Betting News

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Other NFL Week 6 Articles on Betting News

• Commanders vs. Bears Thursday Night Football Betting: Fields, Bears favored to remain perfect at home
• Cowboys vs. Eagles Week 6 Betting: Back the Eagles, Under in Sunday Night Football Rivalry Game